منابع مشابه
Tracing antigen signatures in the human IgE repertoire
Allergen recognition by IgE antibodies is a key event in allergic inflammation. In this study, the IgE IGHV repertoires of individuals with allergy to the major birch pollen allergen, Bet v 1, were analyzed over a four years period of allergen exposure by RT-PCR and sequencing of cDNA. Approximately half of the IgE transcripts represented non-redundant sequences, which belonged to seventeen dif...
متن کاملThe IgE repertoire in patients with food allergy resolved at component level
Methods Serum samples were analysed by microarray Immuno CAP ISAC (Phadia), which allows to detect specific IgE against more than 100 of molecular components. We have retrospectively analyzed 153 patients with proven food allergy, 96 of them being children under 18 years. We recorded occurence of early reactions including OAS and anaphylaxis and also delayed reactions (atopic eczema and eosinop...
متن کاملIgE receptors on human basophils. Relationship to serum IgE concentration.
As reported previously, and confirmed here in 26 donors, the serum IgE level (2.6-5,500 ng/ml) correlates well (rs = 0.95, P less than 0.001) with the in vivo number of IgE molecules/basophil (6,000-600,000). The total number of IgE receptors/basophil was monitored by incubating them with an IgE-rich serum (15 microgram/ml), quantitatively stripping IgE from the cells at pH 3.7, and measuring e...
متن کاملGenetic control of human NK cell repertoire.
Through differential killer cell Ig-like receptor (KIR) and CD94:NKG2 gene expression, human NK cells generate diverse repertoires, each cell having an inhibitory receptor for autologous HLA class I. Using a new method for measuring repertoire difference that integrates multiple flow cytometry parameters, we found individual repertoire stability, but population variability. Correlating repertoi...
متن کاملDopamine receptor repertoire of human granulosa cells
BACKGROUND High levels of dopamine (DA) were described in human ovary and recently evidence for DA receptors in granulosa and luteal cells has been provided, as well. However, neither the full repertoire of ovarian receptors for DA, nor their specific role, is established. Human granulosa cells (GCs) derived from women undergoing in vitro fertilization (IVF) are an adequate model for endocrine ...
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ژورنال
عنوان ژورنال: International Archives of Allergy and Immunology
سال: 2013
ISSN: 1018-2438,1423-0097
DOI: 10.1159/000355947